Article
Genetic abnormalities and HPV status in cervical and vulvar squamous cell carcinomas.
Cancer genetics and cytogenetics - 1 Feb 2005
Huang Fung Yu, Kwok Yvonne K Y, Lau Elizabeth T, Tang Mary H Y, Ng Tong Yow, Ngan Hextan Y S
Abstract excerpt
Cervical and vulvar cancers are diseases of the female lower genital tract, and high-risk human papillomavirus (HPV) infection is the most important risk factor for the development of both cancers. However, it is clear that additional genetic events are necessary for tumor progression, particularly in HPV-negative cases. We detected the presence of high-risk HPV16 and HPV18 genomes by gene-specific polymerase...
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