Article
Transmission/disequilibrium tests for extended marker haplotypes.
American journal of human genetics - 1 Oct 1999
Clayton D, Jones H
Abstract excerpt
A generalization of the transmission/disequilibrium test to detect association between polymorphic markers and discrete or quantitative traits is discussed, with particular emphasis on marker haplotypes formed by several adjacent loci. Furthermore, strategies for testing haplotype association, using methods from spatial statistics, are developed. This approach compares the "similarity" of transmitted and...
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