Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bayesian spatial modeling of haplotype associations.

Human heredity - 1 Jan 2003

Thomas Duncan C, Stram Daniel O, Conti David, Molitor John, Marjoram Paul

Abstract excerpt

We review methods for relating the risk of disease to a collection of single nucleotide polymorphisms (SNPs) within a small region. Association studies using case-control designs with unrelated individuals could be used either to test for a direct effect of a candidate gene and characterize the responsible variant(s), or to fine map an unknown gene by exploiting the pattern of linkage disequilibrium (LD). We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Bayes Theorem
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Data Interpretation, Statistical

Share to Haplotypes

Share to Likelihood Functions

Share to Models, Genetic

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 14614236
DOI: 10.1159/000073730

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bayesian spatial modeling of haplotype associations.PMID 14614236Read ↗

A model-based approach for analysis of spatial structure in genetic data.Semantic proximity Read ↗

A spatial probit model for fine-scale mapping of disease genes.Semantic proximity Read ↗

A Note on the Relations Between Spatio-Genetic Models.Semantic proximity Read ↗

Haplotype block partitioning as a tool for dimensionality reduction in SNP association studies.Semantic proximity Read ↗

Potts model for haplotype associations.Semantic proximity Read ↗

A flexible Bayesian framework for modeling haplotype association with disease, allowing for dominance effects of the underlying causative variants.Semantic proximity Read ↗

Novel probabilistic models of spatial genetic ancestry with applications to stratification correction in genome-wide association studies.Semantic proximity Read ↗

Bayesian graphical models for genomewide association studies.Semantic proximity Read ↗

Modeling linkage disequilibrium and identifying recombination hotspots using single-nucleotide polymorphism data.Semantic proximity Read ↗

Handling marker-marker linkage disequilibrium: pedigree analysis with clustered markers.Semantic proximity Read ↗

Genetic association mapping via evolution-based clustering of haplotypes.Semantic proximity Read ↗

Pedigree tests of transmission disequilibrium.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.