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Article

Relationship between a GABAA alpha 6 Pro385Ser substitution and benzodiazepine sensitivity.

The American journal of psychiatry - 1 Sept 1999

Iwata N, Cowley D S, Radel M, Roy-Byrne P P, Goldman D

Abstract excerpt

OBJECTIVE: In humans, interindividual variation in sensitivity to benzodiazepine drugs may correlate with behavioral variation, including vulnerability to disease states such as alcoholism. In the rat, variation in alcohol and benzodiazepine sensitivity has been correlated with an inherited variant of the GABAA alpha 6 receptor. The authors detected a Pro385Ser [1236C > T] amino acid substitution in the human...

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Source

Identifiers

PMID: 10484961
DOI: 10.1176/ajp.156.9.1447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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