Article
High-throughput single nucleotide polymorphism genotyping by fluorescent 5' exonuclease assay.
BioTechniques - 1 Sept 1999
Morin P A, Saiz R, Monjazeb A
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are the class of DNA variants that are most common in the genome. Technologies are needed that allow relatively high-throughput, high-quality genotyping of SNPs, with rapid assay development for individual SNPs of interest. We have implemented an accurate and high-throughput SNP genotyping system using a commercially available fluorescent 5' exonuclease assay. Optimization...
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