Article
The recombinant 5-HT1A receptor: G protein coupling and signalling pathways.
British journal of pharmacology - 1 Aug 1999
Raymond J R, Mukhin Y V, Gettys T W, Garnovskaya M N
Abstract excerpt
The 5-hydroxytryptamine 5-HT1A receptor was one of the first G protein coupled receptors whose cDNA and gene were isolated by molecular cloning methods. Transfection of the cDNA of this receptor into cells previously bearing no 5-HT receptors has resulted in the acquisition of large amounts of information regarding potential signal transduction pathways linked to the receptor, correlations of receptor structure...
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