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Article

G‐protein‐coupled receptors: past, present and future

1 Jan 2006

Abstract excerpt

The G-protein-coupled receptor (GPCR) family represents the largest and most versatile group of cell surface receptors. Drugs active at these receptors have therapeutic actions across a wide range of human diseases ranging from allergic rhinitis to pain, hypertension and schizophrenia. This review provides a brief historical overview of the properties and signalling characteristics of this important family of...

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PMID: 16402114
DOI: 10.1038/sj.bjp.0706455

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