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Complementation of a Capsule Deficient <i>Cryptococcus neoformans</i> with <i>Cap64</i> Restores Virulence in a Murine Lung Infection

1 Mar 2002

Abstract excerpt

Cryptococcosis is a systemic infection in humans caused by the opportunistic fungal pathogen, Cryptococcus neoformans. The infection usually presents as chronic meningoencephalitis, but infects via the respiratory tract. A polysaccharide capsule is a major virulence factor, which allows the yeast to resist host defenses. However, the essential role of the capsule in allowing it to resist host defenses during the...

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PMID: 11867339
DOI: 10.1165/ajrcmb.26.3.4479

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Complementation of a Capsule Deficient <i>Cryptococcus neoformans</i> with <i>Cap64</i> Restores Virulence in a Murine Lung InfectionPMID 11867339Read ↗

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