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Article

The second capsule gene of cryptococcus neoformans, CAP64, is essential for virulence

1 Jun 1996

Abstract excerpt

The extracellular polysaccharide capsule produced by Cryptococcus neoformans is essential for its pathogenicity. We have isolated and characterized a gene, (AP64, which is required for capsule formation. An encapsulated strain created by complementation of the cap64 mutation produced fatal infection of mice within 25 days, while the cap64 acapsular strain was avirulent. Gene deletion of CAP64 from a wild-type...

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PMID: 8675296
DOI: 10.1128/iai.64.6.1977-1983.1996

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The second capsule gene of cryptococcus neoformans, CAP64, is essential for virulencePMID 8675296Read ↗

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