Article
Longitudinal study of Plasmodium falciparum infection and immune responses in infants with or without the sickle cell trait.
International journal of epidemiology - 1 Aug 1999
Le Hesran J Y, Personne I, Personne P, Fievet N, Dubois B, Beyemé M, Boudin C, Cot M, Deloron P
Abstract excerpt
BACKGROUND: Individuals may be homozygous (SS) or heterozygous (AS) sickle cell gene carriers or have normal adult haemoglobin (AA). Haemoglobin S could have a protective role against malaria but evidence is sparse and the operating mechanisms are poorly known. METHODS: We followed two cohorts of children. The first was enrolled at birth (156 newborn babies) and the second at 24-36 months old (84 children). Both...
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