Article
Sickle cell trait protects against Plasmodium falciparum infection.
American journal of epidemiology - 1 Oct 2012
Billo Mounkaila A, Johnson Eric S, Doumbia Seydou O, Poudiougou Belco, Sagara Issaka, Diawara Sory I, Diakité Mahamadou, Diallo Mouctar, Doumbo Ogobara K, Tounkara Anatole, Rice Janet, James Mark A, Krogstad Donald J
Abstract excerpt
Although sickle cell trait protects against severe disease due to Plasmodium falciparum, it has not been clear whether sickle trait also protects against asymptomatic infection (parasitemia). To address this question, the authors identified 171 persistently smear-negative children and 450 asymptomatic persistently smear-positive children in Bancoumana, Mali (June 1996 to June 1998). They then followed both groups...
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