Article
Anemia Offers Stronger Protection Than Sickle Cell Trait Against the Erythrocytic Stage of Falciparum Malaria and This Protection Is Reversed by Iron Supplementation.
EBioMedicine - 1 Dec 2016
Goheen M M, Wegmüller R, Bah A, Darboe B, Danso E, Affara M, Gardner D, Patel J C, Prentice A M, Cerami C
Abstract excerpt
BACKGROUND: Iron deficiency causes long-term adverse consequences for children and is the most common nutritional deficiency worldwide. Observational studies suggest that iron deficiency anemia protects against Plasmodium falciparum malaria and several intervention trials have indicated that iron supplementation increases malaria risk through unknown mechanism(s). This poses a major challenge for health policy....
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