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Article

Mutational analysis of the PMS2 gene in sporadic endometrial cancers with microsatellite instability.

Gynecologic oncology - 1 Sept 1999

Basil J B, Swisher E M, Herzog T J, Rader J S, Elbendary A, Mutch D G, Goodfellow P J

Abstract excerpt

OBJECTIVE: Approximately 20% of endometrial tumors have a defect in DNA mismatch repair and exhibit microsatellite instability (MSI). We assessed the role of the PMS2 DNA mismatch repair gene in MSI-positive sporadic endometrial tumors. METHODS: We examined 40 sporadic endometrial tumor specimens with MSI. All 15 exons of the PMS2 gene were investigated for sequence alterations by single-strand conformational...

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Source

Identifiers

PMID: 10479499
DOI: 10.1006/gyno.1999.5486

Genes

PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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