Article
Analysis of cyclin D1 (CCND1) allelic imbalance and overexpression in sporadic human pituitary tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 1999
Hibberts N A, Simpson D J, Bicknell J E, Broome J C, Hoban P R, Clayton R N, Farrell W E
Abstract excerpt
Cyclin D1 plays an important role in the regulation of cell progression through G1 of the cell cycle and has been demonstrated to have oncogenic properties. Using RFLP-PCR, an A/G polymorphism within the cyclin D1 (CCND1) gene was analyzed in 151 sporadic human pituitary tumors, of which 60 were...
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