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Article

CCND1 G870A polymorphism with altered cyclin D1 transcripts expression is associated with the risk of glioma in a Chinese population.

DNA and cell biology - 1 Jun 2012

Chen Xiangmei, Zhao Tianshu, Li Li, Xu Chunhui, Zhang Xiaolei, Tse Vincent, Zhang Ting, Liu Xiaoqian, Lu Fengmin

Abstract excerpt

A common polymorphism (G870A) in the exon 4/intron 4 boundary of CCND1 gene has been linked to an alternate transcript, cyclin D1b, which preferentially encodes a protein with an increased transforming capability compared with the full-length D1a. Therefore, the CCND1 G870A polymorphism may influence an individual's susceptibility to the development of certain tumors. In the present study, we investigated the...

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Age of Onset
Asian People
Cyclin D1
Gene Expression Regulation, Neoplastic
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 22304571
DOI: 10.1089/dna.2011.1521

Genes

CCND1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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CCND1 G870A polymorphism with altered cyclin D1 transcripts expression is associated with the risk of glioma in a Chinese population.PMID 22304571Read ↗

Association between the G870A polymorphism of Cyclin D1 gene and glioma risk.Semantic proximity Read ↗

The CCND1 G870A gene polymorphism and brain tumor risk: a meta-analysis.Semantic proximity Read ↗

Cyclin D1 G870A polymorphism and the risk of hepatocellular carcinoma in a Chinese population.Semantic proximity Read ↗

Influence of CCND1 G870A polymorphism on the risk of HBV-related HCC and cyclin D1 splicing variant expression in Chinese population.Semantic proximity Read ↗

Cyclin D1 G870A polymorphism and breast cancer risk: a meta-analysis comprising 9,911 cases and 11,171 controls.Semantic proximity Read ↗

CCND1 G870A polymorphism contributes to breast cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

Cyclin D1 G870A polymorphism is associated with an increased risk of hepatocellular carcinoma in the Turkish population: case-control study.Semantic proximity Read ↗

Cyclin D1 G870A polymorphism and risk of nasopharyngeal carcinoma: a case-control study and meta-analysis.Semantic proximity Read ↗

Tumor susceptibility and prognosis of breast cancer associated with the G870A polymorphism of CCND1.Semantic proximity Read ↗

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The association between CCND1 G870A polymorphism and colorectal cancer risk: A meta-analysis.Semantic proximity Read ↗

Association of CCND1 Gene c.870G>A Polymorphism with Breast Cancer Risk: A Case-ControlStudy and a Meta-Analysis.Semantic proximity Read ↗

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