Article
Mutant p53 in patients with invasive cervical cancer stages IB to IIB.
Gynecologic oncology - 1 May 1995
Kainz C, Kohlberger P, Gitsch G, Sliutz G, Breitenecker G, Reinthaller A
Abstract excerpt
The present study evaluates the prognostic value of mutant p53 protein overexpression in 109 surgically treated cervical cancer stages IB to IIB. Squamous cell carcinoma stages IB, IIA, and IIB were present in 52, 13, and 44 cases, respectively. We performed immunohistochemistry using a monoclona...
Topics
- Adult
- Aged
- Aged, 80 and over
- Carcinoma, Squamous Cell
- Female
- Gene Expression Regulation, Neoplastic
- Genes, p53
- Humans
- Middle Aged
- Multivariate Analysis
- Mutation
- Neoplasm Invasiveness
- Neoplasm Staging
- Prognosis
- Proportional Hazards Models
- Survival Rate
- Tumor Suppressor Protein p53
- Uterine Cervical Neoplasms
