Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunohistochemical detection of mutant p53-suppressor gene product in patients with breast cancer: influence on metastasis-free survival.

Anticancer research - 1 Jan 2000

Hanzal E, Gitsch G, Kohlberger P, Dadak C, Miechowiecka N, Breitenecker G

Abstract excerpt

Overexpression of p53-protein appears to be a common event in primary breast cancer. It has been proposed that the presence of elevated levels of this protein may be an independent prognostic factor and may be important for the ability of a tumor to metastasize. This study was performed to evaluate the influence of immunohistochemically detectable mutant p53-protein on metastasis-free survival of patients with...

Topics

Biomarkers, Tumor
Breast Neoplasms
Carcinoma
Female
Genes, p53
Humans
Immunohistochemistry
Middle Aged
Mutation
Neoplasm Metastasis
Neoplasm Staging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Estrogen

Retrospective Studies

Survival Analysis

Time Factors

Tumor Suppressor Protein p53

Source

Identifiers

PMID: 1295480

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1295480-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunohistochemical detection of mutant p53-suppressor gene product in patients with breast cancer: influence on metastasis-free survival.PMID 1295480Read ↗

The effect of immunohistochemically detected p53 accumulation in prognosis of breast cancer; A retrospective survey of outcome.Semantic proximity Read ↗

p53 oncoprotein as a prognostic indicator in patients with breast cancer.Semantic proximity Read ↗

Relation between p53 overexpression and established prognostic factors in breast cancer.Semantic proximity Read ↗

p53 mutations in matched primary and metastatic human tumors.Semantic proximity Read ↗

Association of immunohistochemical staining for p53 with metastatic progression and poor survival in patients with renal cell carcinoma.Semantic proximity Read ↗

Prognostic value of P53 gene mutations in a large series of node-negative breast cancer patients.Semantic proximity Read ↗

Immunohistochemical detection of mutant p53 protein in regional lymph nodes is associated with adverse outcome in stage II colorectal cancer.Semantic proximity Read ↗

Usefulness of immunohistochemical staining for p53 in the prognosis of breast carcinomas: correlations with established prognosis parameters and with the proliferation marker, MIB-1.Semantic proximity Read ↗

Relationship between p53 expression and other prognostic factors in human breast carcinoma. An immunohistochemical study.Semantic proximity Read ↗

p53 alterations in all stages of breast cancer.Semantic proximity Read ↗

Overexpression of p53 and prognosis in breast cancer.Semantic proximity Read ↗

Worse survival for TP53 (p53)-mutated breast cancer patients receiving adjuvant CMF.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.