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Article

Overexpression of bax in human glioma cell lines.

Journal of neurosurgery - 1 Sept 1999

Vogelbaum M A, Tong J X, Perugu R, Gutmann D H, Rich K M

Abstract excerpt

OBJECT: Cells that lose their ability to undergo apoptosis may promote the development of neoplasms and result in resistance to clinical treatment with DNA-damaging modalities such as radio- and chemotherapy. Four established human glioma cell lines that are resistant to apoptosis were transfected with the proapoptotic gene bax and assessed for their sensitivity to a proapoptotic stimulus. METHODS: Two cell lines...

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Share to Antimetabolites, Antineoplastic
Share to bcl-2-Associated X Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to Genetic Vectors

Share to Glioma

Share to Proto-Oncogene Proteins c-bcl-2

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Source

Identifiers

PMID: 10470825
DOI: 10.3171/jns.1999.91.3.0483

Genes

BAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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