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Population structure of recrudescent Plasmodium falciparum isolates from western Uganda.

Tropical medicine & international health : TM & IH - 1 Jul 1999

Jelinek T, Kilian A H, Westermeier A, Pröll S, Kabagambe G, Nothdurft H D, von Sonnenburg F, Löscher T

Abstract excerpt

It has been proposed that polymorphisms of the Merozoite Surface Protein 1 and 2 (MSP1 and MSP2) and the Glutamate Rich Protein (GLURP) genes can be considered as genetic markers for the genotyping of field populations of Plasmodium falciparum. During a field study on in vivo drug resistance against chloroquine, sulphadoxine/pyrimethamine (S/P) and cotrimoxazole in West Uganda, sensitive and resistant isolates...

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PMID: 10470338
DOI: 10.1046/j.1365-3156.1999.00428.x

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