Article
Plasmodium falciparum msp1, msp2 and glurp allele frequency and diversity in sub-Saharan Africa.
Malaria journal - 6 Apr 2011
Mwingira Felista, Nkwengulila Gamba, Schoepflin Sonja, Sumari Deborah, Beck Hans-Peter, Snounou Georges, Felger Ingrid, Olliaro Piero, Mugittu Kefas
Abstract excerpt
BACKGROUND: The efficacy of anti-malarial drugs is assessed over a period of 28-63 days (depending on the drugs' residence time) following initiation of treatment in order to capture late failures. However, prolonged follow-up increases the likelihood of new infections depending on transmission intensity. Therefore, molecular genotyping of highly polymorphic regions of Plasmodium falciparum msp1, msp2 and glurp...
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