Article
Plasmodium falciparum msp1, msp2 and glurp allele frequency and diversity in sub-Saharan Africa.
Malaria journal - 6 Apr 2011
Mwingira Felista, Nkwengulila Gamba, Schoepflin Sonja, Sumari Deborah, Beck Hans-Peter, Snounou Georges, Felger Ingrid, Olliaro Piero, Mugittu Kefas
Abstract excerpt
BACKGROUND: The efficacy of anti-malarial drugs is assessed over a period of 28-63 days (depending on the drugs' residence time) following initiation of treatment in order to capture late failures. However, prolonged follow-up increases the likelihood of new infections depending on transmission i...
Topics
- Africa South of the Sahara
- Antigens, Protozoan
- Antimalarials
- Base Sequence
- Child
- Child, Preschool
- Drug Combinations
- Gene Amplification
- Gene Frequency
- Genetic Variation
- Genotype
- Humans
- Malaria, Falciparum
- Merozoite Surface Protein 1