Molecular analysis of Plasmodium falciparum recrudescent malaria infections in children treated with chloroquine in Nigeria.

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Article

Molecular analysis of Plasmodium falciparum recrudescent malaria infections in children treated with chloroquine in Nigeria.

The American journal of tropical medicine and hygiene - 1 Jan 2004

Happi C T, Gbotosho G O, Sowunmi A, Falade C O, Akinboye D O, Gerena L, Kyle D E, Milhous W, Wirth D F, Oduola A M J

Abstract excerpt

Parasite genotyping by a polymerase chain reaction was used to distinguish recrudescent from newly acquired Plasmodium falciparum infections in 50 of 160 Nigerian children taking part in a chloroquine efficacy study in Ibadan, Nigeria. A finger prick blood sample was taken from each child before and after treatment to identify recrudescent parasites. By investigating allelic variation in three polymorphic antigen...

Topics

Animals
Antigens, Protozoan
Antimalarials
Child
Child, Preschool
Chloroquine
DNA, Protozoan
Drug Resistance
Genetic Variation
Humans
Infant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Malaria, Falciparum

Merozoite Surface Protein 1

Nigeria

Plasmodium falciparum

Polymerase Chain Reaction

Protozoan Proteins

Recurrence

Source

Open in PubMed

Identifiers

PMID: 14971693

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-14971693-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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