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Article

Molecular analysis of Plasmodium falciparum recrudescent malaria infections in children treated with chloroquine in Nigeria.

The American journal of tropical medicine and hygiene - 1 Jan 2004

Happi C T, Gbotosho G O, Sowunmi A, Falade C O, Akinboye D O, Gerena L, Kyle D E, Milhous W, Wirth D F, Oduola A M J

Abstract excerpt

Parasite genotyping by a polymerase chain reaction was used to distinguish recrudescent from newly acquired Plasmodium falciparum infections in 50 of 160 Nigerian children taking part in a chloroquine efficacy study in Ibadan, Nigeria. A finger prick blood sample was taken from each child before and after treatment to identify recrudescent parasites. By investigating allelic variation in three polymorphic antigen...

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PMID: 14971693

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