Article
Genetic diversity of Plasmodium falciparum and its relationship to parasite density in an area with different malaria endemicities in West Uganda.
Tropical medicine & international health : TM & IH - 1 Aug 2001
Peyerl-Hoffmann G, Jelinek T, Kilian A, Kabagambe G, Metzger W G, von Sonnenburg F
Abstract excerpt
Field populations of Plasmodium falciparum can be effectively genotyped by PCR-amplification of selected fragments of the Merozoite Surface Proteins 1 and 2 (MSP1 and MSP2). Genetic diversity of P. falciparum populations in areas with different transmission levels (holo- vs. mesoendemic) was investigated in Kabarole District, West Uganda. 225 samples positive for P. falciparum were analysed by amplification of...
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