Article
Paraoxonase polymorphism and its effect on male reproductive outcomes among Chinese pesticide factory workers.
American journal of industrial medicine - 1 Sept 1999
Padungtod C, Niu T, Wang Z, Savitz D A, Christiani D C, Ryan L M, Xu X
Abstract excerpt
BACKGROUND: Serum paraoxonase has been associated with the metabolism of organophosphate pesticides in humans. Molecular analysis of the human paraoxonase gene (PON1) has revealed that Arg192 homozygotes have a greater detoxifying capability than Gln192 homozygotes. We examined the effects of PON1 genotypes on male reproductive outcomes and its interaction with exposure to organophosphate pesticides. METHODS: We...
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