Article
Associations of xenobiotic-metabolizing enzyme genotypes PON1Q192R, PON1L55M and CYP1A1*2A MspI with pathological symptoms of a rural population in south Greece.
Xenobiotica; the fate of foreign compounds in biological systems - 1 Oct 2011
Tsatsakis Aristidis M, Androutsopoulos Vasilis P, Zafiropoulos Alexandros, Babatsikou Fotoula, Alegakis Thanasis, Dialyna Ioanna, Tzatzarakis Manolis, Koutis Charilaos
Abstract excerpt
Paraoxonases and cytochromes P450 constitute two major classes of xenobiotic-metabolizing enzymes involved in the detoxification of pesticide chemicals. In this study, we examined the distribution of two common genetic polymorphisms of the paraoxonase 1 gene and one common polymorphism of the CYP1A1 gene, in relation to pathological diseases occurring in a rural population. Blood and hair samples were collected...
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