Article
Blastocyst formation is blocked in mouse embryos lacking the splicing factor SRp20.
Current biology : CB - 26 Aug 1999
Jumaa H, Wei G, Nielsen P J
Abstract excerpt
SRp20 is a splicing factor belonging to the highly conserved family of SR proteins [1] [2] [3] [4], which have multiple roles in the regulation of constitutive and alternative splicing in vivo. It has been suggested that SR proteins are involved in bringing together the splice sites during spliceosome assembly [5]. SR proteins show partial redundancy, as each single SR protein can restore splicing activity to a...
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