Article
Serum response factor is essential for mesoderm formation during mouse embryogenesis.
The EMBO journal - 2 Nov 1998
Arsenian S, Weinhold B, Oelgeschläger M, Rüther U, Nordheim A
Abstract excerpt
The transcription factor serum response factor (SRF), a phylogenetically conserved nuclear protein, mediates the rapid transcriptional response to extracellular stimuli, e.g. growth and differentiation signals. DNA- protein complexes containing SRF or its homologues function as nuclear targets of...
Topics
- Animals
- Calcium-Calmodulin-Dependent Protein Kinases
- Cell Division
- DNA-Binding Proteins
- Embryonic and Fetal Development
- Gene Expression Regulation, Developmental
- Gene Targeting
- Genes, Immediate-Early
- Genetic Markers
- Genotype
- Histocytochemistry
- Immunohistochemistry
- Mesoderm
- Mice
- Mice, Knockout
- Mutation
- Nuclear Proteins
- RNA, Messenger