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Article

Pre-mRNA splicing by the essential Drosophila protein B52: tissue and target specificity.

Molecular and cellular biology - 1 Jan 2000

Hoffman B E, Lis J T

Abstract excerpt

B52, an essential SR protein of Drosophila melanogaster, stimulates pre-mRNA splicing in splicing-deficient mammalian S100 extracts. Surprisingly, mutant larvae depleted of B52 were found to be capable of splicing at least several pre-mRNAs tested (H. Z. Ring and J. T. Lis, Mol. Cell. Biol. 14:7499-7506, 1994). In a homologous in vitro system, we demonstrated that B52 complements a Drosophila S100 extract to...

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Identifiers

PMID: 10594020
DOI: 10.1128/MCB.20.1.181-186.2000
PMCID: PMC85073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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