Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Associations of mitochondrial genomic variation with successful neurological aging.

Mitochondrion - 1 Sept 2024

Tamvaka Nicole, Heckman Michael G, Johnson Patrick W, Soto-Beasley Alexandra I, Walton Ronald L, Koga Shunsuke, Uitti Ryan J, Parfitt Francine, Graff-Radford Michelle R, Wszolek Zbigniew K, Graff-Radford Neill, Valentino Rebecca R, Ross Owen A

Abstract excerpt

Mitochondrial health is an integral factor in aging, with mitochondrial dysfunction known to increase with age and contribute to the development of age-related neurodegenerative disorders. Additionally, the mitochondrial genome (mtDNA) has been shown to acquire potentially damaging somatic variation as part of the aging process, while mtDNA single nucleotide polymorphism (SNPs) have been shown to be both...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Mitochondrial

Share to Genome, Mitochondrial

Share to Haplotypes

Share to Longevity

Share to Nervous System Diseases

Share to Young Adult

Source

Identifiers

PMID: 39179138
DOI: 10.1016/j.mito.2024.101948

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations of mitochondrial genomic variation with successful neurological aging.PMID 39179138Read ↗

Mitochondrial DNA mutations in neurodegeneration.Semantic proximity Read ↗

Mitochondrial DNA sequence variation and neurodegeneration.Semantic proximity Read ↗

Role of mitochondrial DNA in longevity, aging and age-related diseases in humans: a reappraisal.Semantic proximity Read ↗

Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans.Semantic proximity Read ↗

mtDNA mutations in human aging and longevity: controversies and new perspectives opened by high-throughput technologies.Semantic proximity Read ↗

Associations of Mitochondrial Genomic Variation with Corticobasal Degeneration, Progressive Supranuclear Palsy, and Neuropathological Tau MeasuresSemantic proximity Read ↗

Mitochondrial DNA involvement in human longevity.Semantic proximity Read ↗

Associations of mitochondrial genomic variation with corticobasal degeneration, progressive supranuclear palsy, and neuropathological tau measures.Semantic proximity Read ↗

Association between mitochondrial DNA variations and Alzheimer's disease in the ADNI cohort.Semantic proximity Read ↗

Mitochondrial DNA sequence variation associated with dementia and cognitive function in the elderly.Semantic proximity Read ↗

Mitochondrial DNA and traumatic brain injury.Semantic proximity Read ↗

Triad of Risk for Late Onset Alzheimer’s: Mitochondrial Haplotype, APOE Genotype and Chromosomal SexSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.