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Article

Oxidation of guanine in cellular DNA by solar UV radiation: biological role.

Photochemistry and photobiology - 1 Aug 1999

Douki T, Perdiz D, Gróf P, Kuluncsics Z, Moustacchi E, Cadet J, Sage E

Abstract excerpt

The formation of cyclobutane pyrimidine dimers (CPD) and 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo) was investigated in Chinese hamster ovary cells upon exposure to either UVC, UVB, UVA or simulated sunlight (SSL). Two cell lines were used, namely AT3-2 and UVL9, the latter being deficient in nucleotide excision repair and consequently UV sensitive. For all types of radiation, including UVA, CPD were found...

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Identifiers

PMID: 10461457

Genes

CPD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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