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Article

Positive and negative selection of alphabetaTCR+ T cells in thymectomized adult radiation bone marrow chimeras.

Transplantation - 15 Aug 1999

Colson Y L, Abou El-Ezz A Y, Gaines B A, Ildstad S T

Abstract excerpt

BACKGROUND: The mature T-cell repertoire is characterized by the negative selection of potentially autoreactive T cells and the positive selection of T cells restricted to antigen-recognition in the context of self-MHC molecules. It is currently believed that the thymus is critical for these selection events. Although alpha(beta)T cell receptor (TCR)+ T cells have been reported in thymectomized recipients,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10459545
DOI: 10.1097/00007890-199908150-00013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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