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Article

The developmental role of warthog, the notch modifier encoding Drab6.

The Journal of cell biology - 23 Aug 1999

Purcell K, Artavanis-Tsakonas S

Abstract excerpt

The warthog (wrt) gene, recovered as a modifier for Notch signaling, was found to encode the Drosophila homologue of rab6, Drab6. Vertebrate and yeast homologues of this protein have been shown to regulate Golgi network to TGN trafficking. To study the function of this protein in the development of a multicellular organism, we analyzed three different warthog mutants. The first was an R62C point mutation, the...

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Identifiers

PMID: 10459009
DOI: 10.1083/jcb.146.4.731
PMCID: PMC2156142

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