CDC42 and Rac1 control different actin-dependent processes in the Drosophila wing disc epithelium.

doi:10.1083/jcb.131.1.151

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Article

CDC42 and Rac1 control different actin-dependent processes in the Drosophila wing disc epithelium.

The Journal of cell biology - 1 Oct 1995

Eaton S, Auvinen P, Luo L, Jan Y N, Simons K

Abstract excerpt

Cdc42 and Rac1 are members of the rho family of small guanosinetriphosphatases and are required for a diverse set of cytoskeleton-membrane interactions in different cell types. Here we show that these two proteins contribute differently to the organization of epithelial cells in the Drosophila wing imaginal disc. Drac1 is required to assemble actin at adherens junctions. Failure of adherens junction actin...

Topics

Actins
Amino Acid Sequence
Animals
Cadherins
Cell Polarity
Cell Size
Cytoskeletal Proteins
Cytoskeleton
Drosophila
Drosophila Proteins
Epithelial Cells
Epithelium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

GTP Phosphohydrolases

GTP-Binding Proteins

Molecular Sequence Data

Morphogenesis

Mutation

Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 7559772
DOI: 10.1083/jcb.131.1.151
PMCID: PMC2120599

Genes

CDC42

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7559772-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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