Article
The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Jun 1999
Chung W K, Luke A, Cooper R S, Rotini C, Vidal-Puig A, Rosenbaum M, Gordon D, Leal S M, Caprio S, Goldsmith R, Andreu A L, Bruno C, DiMauro S, Heo M, Lowe W L, Lowell B B, Allison D B, Leibel R L
Abstract excerpt
The biological role(s) proposed for UCP3 in energy homeostasis have been based primarily upon amino acid sequence homology to UCP1. Spontaneous mutations of UCP3> have been described in humans, but not in rodents. The functional consequences-or lack thereof-of these mutations in humans will be of great importance in elucidating the biology of this protein. The results of two such studies are summarized here.
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