Article
Simple and accurate PCR-based system for typing vacuolating cytotoxin alleles of Helicobacter pylori.
Journal of clinical microbiology - 1 Sept 1999
Atherton J C, Cover T L, Twells R J, Morales M R, Hawkey C J, Blaser M J
Abstract excerpt
Alleles of the vacuolating cytotoxin gene (vacA) of Helicobacter pylori vary between strains, particularly in the region encoding the signal sequence (which may be type s1 or s2) and the midregion (which may be type m1 or m2). Using a PCR-based typing system developed in the United States, we showed that 36 strains from Asia and South America were all vacA signal sequence type s1; 3 were midregion type m1 and 11...
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