Article
B-cell responses to a peptide epitope: mutations in heavy chain alone lead to maturation of antibody responses.
Immunology - 1 May 1999
Tuteja R
Abstract excerpt
In the present study, the genetic mechanisms responsible for generation of antibodies recognizing the dominant epitope within a synthetic peptide PS1CT3 were examined. PS1CT3 is a peptide model antigen containing residues 28-42 of the large protein of the surface antigen of hepatitis B virus as B epitope (designated PS1), and the known T-helper-cell epitope derived from the circumsporozoite protein of the malaria...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
