B cell responses to a peptide epitope. II: Multiple levels of selection during maturation of primary responses.

doi:10.1038/icb.1997.38

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Article

B cell responses to a peptide epitope. II: Multiple levels of selection during maturation of primary responses.

Immunology and cell biology - 1 Jun 1997

Tuteja R, Agarwal A, Vijayakrishnan L, Nayak B P, Gupta S K, Kumar V, Rao K V

Abstract excerpt

This report analyses murine primary humoral recognition of a linear domain (MEP 17-31) within a 100 amino acid polypeptide, MEP-1. An analysis of the early primary IgM response revealed that MEP 17-31 presented at least two distinct domains for pre-immune B cell recognition represented by MEP-1 r...

Topics

Amino Acid Sequence
Animals
Antibody Specificity
B-Lymphocytes
Base Sequence
Binding Sites
DNA
DNA Primers
Female
Immunodominant Epitopes
Immunoglobulin G
Immunoglobulin M

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Molecular Sequence Data

Peptide Fragments

Phenotype

Polymerase Chain Reaction

Recombinant Fusion Proteins

Source

Open in PubMed

Identifiers

PMID: 9243289
DOI: 10.1038/icb.1997.38

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9243289-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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