Article
TNF and TNFR polymorphisms in severe sepsis and septic shock: a prospective multicentre study.
Genes and immunity - 1 Dec 2004
Gordon A C, Lagan A L, Aganna E, Cheung L, Peters C J, McDermott M F, Millo J L, Welsh K I, Holloway P, Hitman G A, Piper R D, Garrard C S, Hinds C J
Abstract excerpt
Tumour necrosis factor (TNF) is an important pro-inflammatory cytokine produced in sepsis. Studies examining the association of individual TNF single nucleotide polymorphisms with sepsis have produced conflicting results. This study investigated whether common polymorphisms of the TNF locus and t...
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