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Article

Interleukin-1 receptor antagonist gene polymorphism and mortality in patients with severe sepsis.

Clinical and experimental immunology - 1 Feb 2002

Arnalich F, López-Maderuelo D, Codoceo R, Lopez J, Solis-Garrido L M, Capiscol C, Fernandez-Capitán C, Madero R, Montiel C

Abstract excerpt

This study aims to determine the influence of the polymorphism within the intron 2 of the interleukin-1 receptor antagonist gene (IL-1RN*) on the outcome of severe sepsis, and to assess its functional significance by correlating this polymorphism with the total production of interleukin-1 receptor antagonist (IL-1Ra) protein determined in stimulated peripheral blood mononuclear cells (PBMC). A group of 78...

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Identifiers

PMID: 11876758
DOI: 10.1046/j.1365-2249.2002.01743.x
PMCID: PMC1906336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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