Article
[Association of different alleles in interleukin-1 family genes with the coded cytokines production and outcome of sepsis].
Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue - 1 Apr 2005
Yang Ming-shi, Ma Peng-lin, Chen De-chang
Abstract excerpt
OBJECTIVE: To investigate the association of alleles in interleukin-1(IL-1) family genes with IL-1alpha, IL-1beta, IL-1ra production as well as mRNA expression and the outcome of sepsis. METHODS: Sixty septic patients and equal number of healthy volunteers were enrolled in this study. Monocytes of healthy volunteers segregated by Ficoll were stimulated by lipopolysaccharide (LPS) in vitro. IL-1alpha, IL-1beta and...
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