Article
Control of the terminal step of intracellular membrane fusion by protein phosphatase 1.
Science (New York, N.Y.) - 13 Aug 1999
Peters C, Andrews P D, Stark M J, Cesaro-Tadic S, Glatz A, Podtelejnikov A, Mann M, Mayer A
Abstract excerpt
Intracellular membrane fusion is crucial for the biogenesis and maintenance of cellular compartments, for vesicular traffic between them, and for exo- and endocytosis. Parts of the molecular machinery underlying this process have been identified, but most of these components operate in mutual recognition of the membranes. Here it is shown that protein phosphatase 1 (PP1) is essential for bilayer mixing, the last...
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