Article
Late stages of the synchronized macrophage fusion in osteoclast formation depend on dynamin
22 Oct 2014
Abstract excerpt
Macrophage fusion that leads to osteoclast formation is one of the most important examples of cell-cell fusion in development, tissue homoeostasis and immune response. Protein machinery that fuses macrophages remains to be identified. In the present study, we explored the fusion stage of osteoclast formation for RAW macrophage-like murine cells and for macrophages derived from human monocytes. To uncouple fusion...
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