Article
The bacteriophage T4 anti-sigma factor AsiA is not necessary for the inhibition of early promoters in vivo.
Molecular microbiology - 1 Mar 2000
Pène C, Uzan M
Abstract excerpt
Bacteriophage T4 early promoters are utilized immediately after infection and are abruptly turned off 2-3 min later (at 30 degrees C) when the middle promoters are activated. The viral early protein AsiA has been suspected to bring about this transcriptional switch: not only does it activate transcription at middle promoters in vivo and in vitro but it also shows potent anti-sigma70 activity in vitro, suggesting...
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