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Article

Impact of apolipoprotein E epsilon4 and vascular disease on brain morphology in men from the NHLBI twin study.

Stroke - 1 Aug 1999

DeCarli C, Reed T, Miller B L, Wolf P A, Swan G E, Carmelli D

Abstract excerpt

BACKGROUND AND PURPOSE: Apolipoprotein E epsilon4 genotype (ApoE4) has been associated with increased risk for cardiovascular disease morbidity or mortality. This appears to be mediated by an ApoE4-related increase in cardiovascular atherosclerosis. Given the similarities between risk factors for heart disease and risk factors for stroke, a positive association between ApoE4 and stroke would be expected. Since...

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Source

Identifiers

PMID: 10436099
DOI: 10.1161/01.str.30.8.1548

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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