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Article

Naloxone retards the expression of a genetic predisposition toward alcohol drinking.

Psychopharmacology - 1 Jun 1999

Badia-Elder N E, Mosemiller A K, Elder R L, Froehlich J C

Abstract excerpt

OBJECTIVE: This study examined whether repeated daily treatment with naloxone prevents expression of a genetic predisposition toward high alcohol drinking in rats selectively bred for alcohol preference (P line). METHODS: In phase 1, alcohol-naive male rats were given food and water ad libitum and were pretreated with naloxone (2.5, 5.0, or 10.0 mg/kg, IP) or saline prior to scheduled access to alcohol (2 h/day)...

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Identifiers

PMID: 10435386
DOI: 10.1007/s002130050995

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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