Article
Familial versus sporadic longevity and MHC markers.
Journal of biological regulators and homeostatic agents - 1 Jan 2000
Henon N, Busson M, Dehay-Martuchou C, Charron D, Hors J
Abstract excerpt
We have studied the polymorphism of HLA-A, B, in 2 elderly populations (> or = 90 years) compared to a control series of 429 healthy unrelated individuals less advanced in age. The aged population issued from the CHRONOS cohort consisted of 336 centenarians without familial history of longevity, and 102 nonagenarians index cases randomly selected from families. Almost all individuals (310) were previously typed...
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