Article
Telomere Length, HLA, and Longevity-Results from a Multicenter Study.
International journal of molecular sciences - 30 Aug 2024
Dratwa-Kuzmin Marta, Hadra Bushra Al, Oguz Fatma, Ogret Yeliz, Constantinescu Ileana, Apostol Dimitri, Talangescu Adriana, Constantinescu Alexandra-Elena, Maruntelu Ion, Kościńska Katarzyna, Lukanov Tsvetelin, Naumova Elissaveta, Bogunia-Kubik Katarzyna
Abstract excerpt
Aging is an exceptionally complex process that depends on genetic, environmental, and lifestyle factors. Previous studies within the International HLA and Immunogenetics Workshop (IHIWS) component "Immunogenetics of Ageing" showed that longevity is associated with positive selection of HLA-DRB1*11- and DRB1*16-associated haplotypes, shown to be protective against diseases. Within the 18th IHIWS, we aimed to...
Topics
- Humans
- Longevity
- Aged
- Middle Aged
- Male
- Adult
- Female
- Aged, 80 and over
- Adolescent
- HLA Antigens
- Young Adult
- Telomere
- Alleles
- Telomere Homeostasis