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Article

Homozygous MHC genotypes and longevity.

Human heredity - 1 Jan 2000

Dorak M T, Mills K I, Gaffney D, Wilson D W, Galbraith I, Henderson N, Burnett A K

Abstract excerpt

To investigate the relevance of the major histocompatibility complex (MHC) in longevity, we carried out a molecular analysis of the MHC in 432 unrelated healthy individuals. The comparison of individuals < or = 25 years and > 25 years showed that the 5.8-kb DQA1 allele, which corresponds to HLA-D...

Topics

Adult
Age Factors
Aged
Alleles
Female
Gene Frequency
HLA-DQ Antigens
HLA-DQ alpha-Chains
Homozygote
Humans
Longevity
Major Histocompatibility Complex
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

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Identifiers

PMID: 7927356
DOI: 10.1159/000154229

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7927356-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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