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Article

Longevity and heredity in humans. Association with the human leucocyte antigen phenotype.

Annals of the New York Academy of Sciences - 1 Jan 1991

Lagaay A M, D'Amaro J, Ligthart G J, Schreuder G M, van Rood J J, Hijmans W

Abstract excerpt

Several arguments support the idea of a link between longevity and heredity, both in experimental animals and in the human species. In mice, genes in the major histocompatibility complex (MHC) are associated with a significant effect on life span. Results of analogous studies in man are confusing and contradictory. We have therefore investigated the question of an association of the human leucocyte antigen (HLA)...

Topics

Adult
Aged
Aged, 80 and over
Female
HLA Antigens
Histocompatibility Testing
Humans
Longevity
Male
Netherlands
Phenotype
Sex Characteristics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1859103
DOI: 10.1111/j.1749-6632.1991.tb16970.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1859103-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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