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Article

Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells.

The Journal of investigative dermatology - 1 Jan 2009

Zaba Lisa C, Fuentes-Duculan Judilyn, Eungdamrong Narat John, Abello Maria Veronica, Novitskaya Inna, Pierson Katherine C, Gonzalez Juana, Krueger James G, Lowes Michelle A

Abstract excerpt

Myeloid dermal dendritic cells (DCs) accumulate in chronically inflamed tissues such as psoriasis. The importance of these cells for psoriasis pathogenesis is suggested by comparative T-cell and DC-cell counts, where DCs outnumber T cells. We have previously identified CD11c(+)-blood dendritic cell antigen (BDCA)-1(+) cells as the main resident dermal DC population found in normal skin. We now show that psoriatic...

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Identifiers

PMID: 18633443
DOI: 10.1038/jid.2008.194
PMCID: PMC2701224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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