Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CD8alpha+ and CD8alpha- subclasses of dendritic cells direct the development of distinct T helper cells in vivo.

The Journal of experimental medicine - 1 Feb 1999

Maldonado-López R, De Smedt T, Michel P, Godfroid J, Pajak B, Heirman C, Thielemans K, Leo O, Urbain J, Moser M

Abstract excerpt

Cells of the dendritic family display some unique properties that confer to them the capacity to sensitize naive T cells in vitro and in vivo. In the mouse, two subclasses of dendritic cells (DCs) have been described that differ by their CD8alpha expression and their localization in lymphoid organs. The physiologic function of both cell populations remains obscure. Studies conducted in vitro have suggested that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen Presentation
Share to CD8 Antigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interferon-gamma

Share to Lymphocyte Activation

Share to Mice, Inbred BALB C

Share to Mice, Mutant Strains

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 9927520
DOI: 10.1084/jem.189.3.587
PMCID: PMC2192907

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CD8alpha+ and CD8alpha- subclasses of dendritic cells direct the development of distinct T helper cells in vivo.PMID 9927520Read ↗

The CD8+ dendritic cell subset.Semantic proximity Read ↗

DC subsets in positive and negative regulation of immunity.Semantic proximity Read ↗

Dendritic cells as gatekeepers of tolerance.Semantic proximity Read ↗

Comparative genomics as a tool to reveal functional equivalences between human and mouse dendritic cell subsets.Semantic proximity Read ↗

Depending on their maturation state, splenic dendritic cells induce the differentiation of CD4(+) T lymphocytes into memory and/or effector cells in vivo.Semantic proximity Read ↗

The ontogenetic path of human dendritic cells.Semantic proximity Read ↗

Human dendritic cell subsets: An updated view of their ontogeny and functional specialization.Semantic proximity Read ↗

Dendritic cells: phenotypic and functional heterogeneity.Semantic proximity Read ↗

Phenotypic and functional differences of dendritic cells in tumor.Semantic proximity Read ↗

Origin, Phenotype, and Function of Mouse Dendritic Cell Subsets.Semantic proximity Read ↗

Dendritic cells in vivo and in vitro.Semantic proximity Read ↗

Concept of lymphoid versus myeloid dendritic cell lineages revisited: both CD8alpha(-) and CD8alpha(+) dendritic cells are generated from CD4(low) lymphoid-committed precursors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.